PHD at Humboldt University Berlin, Germany
Gabriele Saretzki, PhD, is a Visiting Lecturer in Ageing Research at Newcastle University. With a PhD in Molecular Biology from Humboldt University Berlin and a Masters in Genetics from State University St. Petersburg, she has extensive experience in ageing and health research. She served as a Lecturer at Newcastle University from 2002 to 2021 and has held various research positions in Germany. An editor for multiple scientific journals, she has contributed significantly to the field through her work on telomeres, telomerase, and mitochondrial research. Dr. Saretzki has supervised numerous postgraduate students and secured funding for innovative ageing research projects. Biosciences
Professional Profiles
Education
1990: PhD in Molecular Biology (Magna cum Laude), Humboldt University Berlin, Germany 1982: Masters/Diploma in Genetics (First Grade), State University St. Petersburg, Russia Biosciences
Work Experience
Visiting Lecturer in Ageing Research, Newcastle University, UK Qualifications. Previous Posts 2002-2021: Lecturer in Ageing Research, Newcastle University, UK 2001-2002: Senior Research Assistant, Institute for Ageing and Health, Newcastle University 1999-2001: Research Assistant, University Clinics for Gynaecology, University Freiburg, Germany 1989-1999: Research Assistant, Institute of Pathology, Charite’ Berlin, Humboldt University Berlin, Germany 1996: 3 months as Visiting Scientist at Geron Corporation, USA 1994-1995: Postdoctoral Research Fellowship from Friedrich Jung Foundation, Hamburg at the Institute of Pathology at the Technical University Munich, Germany 1986-1989: PhD Student, Department of Genetics, Humboldt University Berlin, Germany 1982-1986: Junior Research Associate, Department of Genetics, Humboldt University Berlin, Germany Biosciences
Teaching Experience
UG Course “Biology of Ageing” Lectures: Telomeres and telomerase in ageing and disease, Mitochondria in health, mitochondria in disease (2010-2021) MRES Course “Ageing” Lectures: Telomerase in ageing and disease, Stem cell ageing (2011-2021) MRES Course “Stem Cells and Regeneration” Lecture: Stem cell ageing (2012-2021) MRES Course “Cell Cycle” Lecture: Telomeres in ageing and disease (2018-2020)
Postgraduate and Graduate Supervision
Supervised 9 PhD students, 3 MPhil students, approximately 13 MRES/MSc students, and around 40 undergraduates and international ERASMUS students.
Research Focuse
Gabriele Saretzki, PhD, focuses her research on the role of telomeres and telomerase in ageing and neurodegenerative diseases. Her work explores how telomere dysfunction can lead to senescence or apoptosis, and investigates telomerase activity using TRAP assays. She has extensively studied the implications of telomerase in the brain, particularly its potential in ameliorating neurodegenerative conditions such as Parkinson’s Disease. Dr. Saretzki also examines DNA damage in adipocytes and the effects of nutritional interventions. Her research contributions extend to the use of CRISPR/Cas technology in telomere and telomerase studies, highlighting its potential in cancer therapy. Biosciences
Publications
- Author Correction: The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo, Publication date: 2024.
- Measuring telomerase activity using TRAP assays, Publication date: 2024.
- Doing the Unthinkable: Telomerase in the Brain and in Neurodegeneration 21st Century Pathology,Publication date: 2022.
- Senescence and DNA Damage in Adipocytes and Fat Tissues and Its Potential Amelioration through Nutritional Interventions, Publication date: 2022.
- Telomerase in Brain and its Implications in Neurodegenerative Diseases, Publication date: 2021.
- Telomerase Improves PD Symptoms and Pathology, Publication date: 2021.
- The telomerase connection of the brain and its implications for neurodegenerative diseases, Publication date: 2023.
- Telomerase and neurons: an unusual relationship, Publication date: 2022.
- The wonderful new world of telomerase in the brain and its possible implications for neurodegenerative diseases, Publication date: 2020.
- CRISPR/Cas: a new tool in the research of telomeres and telomerase as well as a novel form of cancer therapy, Publication date: 2022.
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