Assist. Prof. Dr. Fekadu Muleta | Computational Methods | Editorial Board Member

Assistant professor (PhD) at Wolaita Sodo university, Ethiopia

Dr. Fekadu Muleta is an Assistant Professor in the Department of Chemistry at Adama Science and Technology University (ASTU), Ethiopia. With a PhD in Bioinorganic Chemistry, his research spans across synthesis, characterization, and biological applications of metal complexes. His academic journey includes a Master’s in Inorganic Chemistry from Bahir Dar University (BDU), where he also completed his Bachelor’s degree in Chemistry. Dr. Muleta has been actively involved in both teaching and research, contributing significantly to the fields of coordination chemistry, biochemistry, and biological chemistry. His scientific approach integrates molecular docking, antimicrobial testing, and the development of novel complexes for anti-cancer applications. His work has been published in several prestigious journals, and he continues to make strides in his area of expertise with a focus on natural product-based ligands.

🎓Profile

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📚 Early Academic Pursuits

Dr. Fekadu Muleta’s academic journey began with a strong foundation in Chemistry at Bahir Dar University (BDU), Ethiopia. His interest in chemistry was evident early on, earning him a Bachelor’s degree in Science Chemistry from BDU in 2007. Following his undergraduate studies, he pursued a Master’s degree in Inorganic Chemistry, specializing in coordination chemistry and biochemistry. Under the mentorship of Prof. Girma Kibatu, his thesis focused on public health issues, specifically analyzing iodine deficiency disorders and iodized salt consumption levels among school children in Amuma and Minjo Districts in Beneshangul Gumuz, Ethiopia. This research, conducted from 2010 to 2011, laid the groundwork for his later transition into research that integrates chemistry with biological applications.

🎓 Professional Endeavors

Dr. Muleta’s professional path took a decisive step forward with his appointment as an Assistant Professor at Adama Science and Technology University (ASTU). Here, he advanced his expertise in Bioinorganic Chemistry, Biochemistry, and Inorganic Chemistry. His Ph.D. dissertation, titled “Synthesis, Characterization, and Molecular Docking Studies of Homoleptic and Heteroleptic Zinc(II), Copper(II), Nickel(II) Complexes of Semicarbazone and Thiosemicarbazone Derivative Ligands for Biological Application”, was supervised by Prof. Tegene Desalegn. This work combined his deep interest in organic ligands, metal complexes, and their biological potential, an area where his academic and professional interests converge.

🔬 Contributions and Research Focus

Dr. Muleta’s research is a blend of synthetic chemistry, biological applications, and advanced analytical techniques. His primary research focuses on the synthesis and characterization of semicarbazone and thiosemicarbazone derivative organic ligands derived from natural products. He has extensively worked on metal complexes, such as zinc, copper, and nickel, exploring their potential as antimicrobial agents, free radical scavengers, and even anti-cancer compounds. In particular, his investigations into heteroleptic and homoleptic complexes have led to novel discoveries that contribute significantly to the understanding of bioinorganic chemistry. Furthermore, Dr. Muleta’s expertise in molecular docking studies offers a crucial link between theoretical chemistry and practical biological applications, a critical area for drug discovery.

🌍 Impact and Influence

Dr. Muleta has had a profound impact on both academic research and the scientific community, particularly in Ethiopia. Through his innovative studies on metal complexation and biological activity, he has contributed to the broader field of medicinal chemistry, with applications that may influence drug design, environmental monitoring, and health sciences. His publications in peer-reviewed journals, such as the Journal of Molecular Structure and the Journal of Chemistry, are a testament to his ability to push the boundaries of both synthetic chemistry and biochemistry.

📑 Academic Citations

Dr. Muleta’s research has already garnered significant recognition in the academic community. Some of his highly cited publications include:

1. Synthesis, characterization, in-silico, and in-vitro biological studies of Cu(II), Zn(II) complexes of semicarbazone, thiosemicarbazone derivatives of dehydrozingerone published in the Journal of Molecular Structure, 2022.
2. Synthesis, molecular docking, and biological studies of novel heteroleptic Cu(II) and Zn(II) complexes of natural product-based semicarbazone derivatives published in 2023, which highlights his interdisciplinary approach integrating chemistry and biology.

These publications have established Dr. Muleta as a valuable contributor to the growing body of knowledge on bioinorganic chemistry and its biological applications, with the potential to lead to therapeutic advancements.

🛠️ Technical Skills

Dr. Muleta’s technical expertise spans a range of sophisticated analytical techniques and platforms. His proficiency in advanced spectroscopy (e.g., Nuclear Magnetic Resonance (NMR), Infrared (IR), UV-Visible Spectroscopy), mass spectrometry, and X-ray Diffraction (XRD) allows him to accurately characterize chemical compounds at the molecular level. Additionally, he is skilled in Differential Scanning Calorimetry (DSC) and Thermogravimetric Analysis (TGA), tools essential for studying the thermal properties of materials. His use of computational tools for molecular docking further complements his empirical research, providing a holistic approach to complex biological questions.

🧑‍🏫 Teaching Experience

As an Assistant Professor at Adama Science and Technology University, Dr. Muleta has had the privilege of shaping the next generation of chemists. He teaches courses related to inorganic chemistry, bioinorganic chemistry, and biochemistry, instilling in his students not only a deep understanding of the subject matter but also a passion for scientific discovery. His ability to translate complex concepts into digestible lessons has made him a respected educator, and his mentorship has inspired many students to pursue careers in research and academia. Dr. Muleta’s work in research and teaching goes hand-in-hand, as he involves his students in cutting-edge research projects, fostering an environment of hands-on learning.

🔮 Legacy and Future Contributions

Looking ahead, Dr. Muleta’s research trajectory promises further innovations in bioinorganic chemistry. He is well-poised to make significant strides in the synthesis of novel metal-based complexes with potential biological applications, particularly in the development of new drugs and antimicrobial agents. His work on crystal growth and solid-state chemistry is expected to contribute to material science, while his continued collaboration with international research communities will expand his global influence.

Top Noted Publications📖

Synthesis, In Silico, and Biological Applications of Novel Heteroleptic Copper (II) Complex of Natural Product-Based Semicarbazone Ligands